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A 10% KOH (w/v) digestion solution was added to each vial (Zhang et al., 2019)

The persistent accumulation of ROSarising from endogenous sources (e.g., mitochondrial leakage, enzymatic reactions) and exogenous insults (e.g., ultraviolet radiation, pollutants, tobacco)can overwhelm the antioxidant defense threshold, triggering widespread oxidative damage targeting proteins, lipids, and nucleic acids

Characterization of mTORC1 signaling pathway of MRD developed in vivo

Antibiotics including rifaximin and metronidazole have been investigated for their capacity to inhibit TMAO formation by targeting gut bacteria that create TMA