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Self Assembled CopperAmino Acid Nanoparticles for in Situ Glutathione AND H2O2 Sequentially Triggered Chemodynamic Therapy Journal of the American Chemical Society Copper homeostasis and copper induced cell death in the pathogenesis of cardiovascular disease and therapeutic strategies PMC Heavy Metal Detox: Can Glutathione Help? Intelligent Labs Cuproptosis: Unraveling the Mechanisms of Copper Induced Cell Death and Its Implication in Cancer Therapy

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Data were extracted into a standardized table capturing Study design, Sample size and population, Intervention or exposure (e.g., antioxidant agent, mitochondrial marker), Outcomes (e.g., pain, fatigue, oxidative markers), Key findings relevant to the PICO questions above

Sci Rep 16 , 14210 (2026)

Prefrontal cortex infusion of beta-hydroxybutyrate, an endogenous NLRP3 inflammasome inhibitor, produces antidepressant-like effects in a rodent model of depression