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Accordingly, a marginal alteration in the intracellular concentration of GSH may not influence the catalytic activities of seleno-GPxs under in vivo conditions

At the same time , these studies explore how copper-bound peptides participate in regulatory signaling networks that support cellular stability

For example, the cleavage site may be too close to ordered structure in the target protein." The problem is especially severe for oligomeric proteins

During mitochondrial glutaminolysis, glutamine is transported into the mitochondrial matrix via the mitochondrial glutamine transporter SLC1A5 variant and then converted to glutamate (Glu) by glutaminase (GLS), releasing ammonium ions [80]