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Topically applied GHK as an anti-wrinkle peptide: Advantages, problems and prospective

For example, cholesterol suppresses the activity of Kir1.1, Kir2.1, Kir4.1, GIRK1 (with the pore mutation F137S), and Kir6.236 (the C-terminal truncation mutant of Kir6.2) (Rosenhouse-Dantsker et al., 2010)