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405,406,407 In addition to fat intake, the overintake of fructose may also impair hepatic insulin sensitivity, and several metabolic pathways are independent of increased weight gain and caloric intake

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Briefly, independent cultures of Agrobacterium carrying pTRV1 or pTRV2-based constructs were resuspended in 10 mM MgCl 2 , 10 mM MES (pH 5.6) and 150 M acetosyringone at OD 600 = 0.8, and incubated for 2 h at 28 C in the dark