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Nonetheless, due to biological and physiological differences between a small animal model and humans, such as a thinner cartilage, possible spontaneous healing of defects, biomechanics, and physical loading in small animals, thus, an additional chondral defect repair study using minipigs should be conducted to confirm these effects

After selecting the regions of interest (ROIs), the m/z and peak intensity list were exported as text files and imported into MarkerView software (Sciex, version 1.2.1) for peak alignment (mass tolerance: 5 ppm

2020), a finding consistent with observations from Western countries where individuals with depression and older adults also display elevated Hcy levels (Whiteman and Moore 2009)