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Description

Obesity has emerged as a major and potentially preventable risk factor for OA

Weight loss tends to pick up speed after titrating to higher doses, and results typically keep building over the first twelve months

The pituitary gland and hypothalamus were collected and frozen for analysis of mRNA expression of GH, GHRH, GHSR, SST, and SSTR by real-time polymerase chain reaction (RT-PCR) and protein expression by Western immunoblotting