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These models allow for transmigration studies as well as more precise measurements of TEER making them very useful in permeability studies and reduces the number of cells needed for the model [117]

Disengagement, fatigue and inconsistent reporting can introduce variability that is difficult to detect when systems are viewed in isolation

Arredouani A

Consistent with physiological changes (such as decreased blood perfusion or sluggish excretion), PET imaging detected kidney filtration alterations and was more sensitive than Cr examinations