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Although a huge number of experimental and preclinical investigations have provided encouraging results, clinical trials must be performed and completed to definitely evaluate the usefulness and risks of targeting IGF-1R as an option in cancer treatment of humans

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IGF-1 LR3 is recommended to patients with the following conditions: hormone deficiency in children that results in short stature, adult growth deficiency, short bowel syndrome, short stature due to Turner Syndrome, adult deficiency associated with pituitary tumors or treatment of these tumors and muscle-wasting disease related to HIV/AIDS [10]