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Zhang J, Ma W, Yin F, Park Y, Zhu KY, Zhang X

However, adverse effects may limit the treatment potential, e.g., glitazones are associated with phenotypical weight gain [136] and obeticholic acid induced pruritus and elevated LDL-C [137], the latter a potential concern in patients already at risk for cardiovascular disease

Nitrogen and sulfur metabolism The pathway analysis revealed that the genes for respiratory nitrate (i.e., narHGJ ) and nitrite reductases (i.e., nirBD ) were down-regulated by DSF (-1.8 to -2.6) and DDTC ( 2.5 to 4.3)