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Arzneimittelforschung 62 (5), 222229

Metabolomics of carotenoids: The challenges and prospectsA review

Shklar and coworkers (173) examined the effects of methotrexate on hamster buccal pouch carcinomas generated by 9,10-dimethyl-l,2-benzanthracene and found that the methotrexate-treated group reported tumors that were larger and more anaplastic and that they progressed more quickly than the control group