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2025;4:100673 DOI: Received: January 07, 2025 Accepted: February 11, 2025 Published: February 24, 2025 Academic Editor: Marcello Iriti, Milan State University, Italy The article belongs to the special issue Medicinal Plants and Bioactive Phytochemicals in Neuroprotection Neurodegenerative disorders, including Alzheimers, Parkinsons, Huntingtons, and amyotrophic lateral sclerosis, are among the most significant health concerns worldwide, characterized by neuronal dysfunction, oxidative stress, neuroinflammation, and protein misfolding

PMC 4882104

Ong KW, Hsu A, Tan BKH

Binding free energy calculation Among the various available approaches for binding free energy predictions, the molecular mechanics generalized Born surface area (MM/GBSA) method has been suggested to provide the rational results 54,55