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Description

CD40 ligand-dependent T cell activation: requirement of B7CD28 signaling through CD40

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Our identification and mapping of the cyclin D-Rb docking interaction provides an additional target for cancer drugs because deregulation of the G1/S transition and the cyclin D-CDK4/6-Rb pathway is a hallmark of many cancer cells 13

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Elderly Clients: The elderly may require increased dosages of some of the B vitamins, such as B12, since absorption worsens with age

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PMID 24683506

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