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Pharmacological effects of gallic acid in health and diseases: a mechanistic review

The expression of SIRT2 is upregulated in the cecal ligation and puncture (CLP)-induced SAKI mouse model and in LPS-treated HK-2 cells, accompanied by significant tubular damage, characterized by the detachment of RTECs, tubular dilation, and epithelial cell flattening

In other studies anemia accompanying the presence of anti-lactoferrin antibodies was characterized on the basis of diminished hemoglobin concentrations, elevated erythrocyte sedimentation rates (ESR) and/or a higher red blood cell distribution width (RDW) as for example in rheumatoid arthritis and SLE (Chikazawa et al., 2000