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In a previous study, most patients in a TAO cohort had mild TAO, whereas 5%6% of patients had moderate to severe TAO (336)

[DOI] [PMC free article] [PubMed] [Google Scholar] 57.Fusco R., Siracusa R., Peritore A.F., Gugliandolo E., Genovese T., DAmico R., Cordaro M., Crupi R., Mandalari G., Impellizzeri D., et al

European Medicines Agency (EMA) approval pathways for peptides are generally similar to FDA processes, facilitating concurrent development for both markets

It has been speculated that the limitations of the effect of antipsychotics on neurogenesis may be associated with an insufficient treatment response in terms of negative and cognitive symptoms, as well as a deteriorating course of schizophrenia