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2 The intrinsic resistance is mediated by the inherent or endogenous characteristics that are exist in tumor cells or tissues prior to initial treatment, such as effective DNA damage repair mechanisms, tumor growth kinetics and stem cell like properties, that offer cancer cells survival benefits and ability to adapt to primary therapeutic stress

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For example: In a 1998 study published in the European Journal of Endocrinology , researchers found that ipamorelin stimulated the release of growth hormone in rats and pigs without raising cortisol (also known as the stress hormone), which other peptides are known to do

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Allow vials to reach room temperature before opening (15 to 30 minutes) Disinfect rubber stoppers with alcohol and allow complete evaporation Inject bacteriostatic water slowly down the vial wall, never directly onto powder Swirl gently to dissolve

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