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For parameter estimation, the maximum-likelihood approach is used

doi: 10.1016/j.redox.2020.101799 11 Opazo-RiosLMasSMarin-RoyoGMezzanoSGomez-GuerreroCMorenoJAet al

All these proteins in Supplementary Table 10 are predicted as binding with MH by the DStruBTarget model that has been developed based on the fusion of protein-drug interaction and ligand similarity methods