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The two exhibit an antagonistic effect through transport competition, regulation of cell death, and balance of the antioxidant system

HDFA treatment targets the blockage in the transportation of folate into the brain through the folate receptor alpha caused by blocking or binding autoantibodies (Frye et al., Overall, this study provides some insight to the potential benefits of safe and well-tolerated therapies that target specific metabolism abnormalities associated with ASD

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In light of these findings, our study aims to assess the regulatory functions of ferroptosis and mitophagy/CMA in the pathogenesis of OA