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112 , E156165 (2015)

Blood tests on admission showed neutrophil leukocytosis at 18.510 9 /L, elevated C-reactive protein at 210mg/L and bicarbonate of 24 mmol/L

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25 As the first enzyme in the transsulfuration pathway, CBS has a SAM regulatory site and mutation at this site results in homocystinuria, 30 which is closely associated with cancer