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Of the WNT genes, WNT7A and WNT10A are more likely to be elevated [137,141,142], although in the Tsk1 mouse model of skin fibrosis, Wnt2, Wnt9a, Wnt10b, and Wnt11 are increased [143]

The increment in intestinal permeability is another prominent mechanism in the gut-brain axis communication in patients with migraine, leading to inflammation and the release of pro-inflammatory cytokines (200, 201)

Although localized to peroxisomes, CROT is essential for transport of medium and long length acyl-CoA chains from peroxisomes to the cytosol and mitochondria for further degradation 83

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