glutathione synthesis in plants Arabidopsis mutants impaired biosynthesis exhibit higher sensitivity towards the glucosinolate hydrolysis product allyl-isothiocyanate Glutathione in Higher Plants: Biosynthesis

Loree JM, Korphaisarn KK, Lam M, Morris VK, Raghav KP, Overman MJ, Eng C, Dasar A, Kee BK, Fogelman D, Wolff RA, Shaw K, Broaddus R, Routbort MJ, Luthra R, Maru DM, Menter DG, Meric-Bernstam F, Kopetz S

Bastonini E, Kovacs D, Picardo M

E., Asarian, L., Dahl, K., Lutz, T

(88) in an 8-week randomized double-blind, placebo-controlled trial with 80 individuals experiencing episodic migraines, discovered that the combination of omega-3 PUFAs and nano-curcumin significantly reduced migraine attack frequency and serum levels of IL-1 in a synergistic manner, though the initial significant reduction in IL-1 gene expression did not remain significant after Bonferroni corrections