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Although high selectivity of PAG for CSE over CBS has been reported (i.e., an IC 50 of 40 M for the CSE-catalyzed reaction using 1 mM of cysteine as the substrate, with no detectable inhibition of CBS even at 10 mM PAG), it also inhibits several other PLP enzymes, such as aspartate aminotransferase, alanine aminotransferase, and methionine -lyase (Sun et al., 2009)

In dermatology practice, it is mainly used in the treatment of dermatocompulsions and pseudoporphyria.8,9 In a non-randomized trial with 30 Egyptian women, one group (n = 10) received oral glutathione 500 mg/day, while another used topical glutathione 2%, and a third used placebo for four weeks, always associated with SPF 30 sunscreen

Micronucleus cytome assay

Vitamin B12 , or cobalamin, is a type of B vitamin