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In a 2014 study published in the Journal of Pharmacology and Experimental Therapeutics , Benoist and colleagues used the HGF/c-Met dimerization antagonist Hinge to block Dihexas effects in scopolamine-impaired rats, demonstrating that the procognitive activity requires functional hepatocyte growth factor (HGF) / mesenchymal-epithelial transition factor (c-Met) receptor signaling [3]

Diagnosis may be difficult and often involves a combination of blood tests, urine tests, and a liver biopsy

CCK-8, DAPI, and DPPH kits, Calcein-AM/PI staining kit and paraformaldehyde (4 %) were purchased from Biyuntian Biotechnology Co

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