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Its activity decreases due to insufficient concentrations of oxygen, that is a co-substrate in the reaction of hydroxylation of HIF-1 (Kim et al., 2021)

Additionally, the RNA-sequencing of L-Cn-treated PBMCs and the GSE62595 dataset can only show the transcriptome changes at the overall level, further studies on exploring the modulation mechanism of L-Cn on a single set of cells should be taken to dissect the related signaling pathway

examined the effect of parenteral xylitol infusion during a euglycemic hyperinsulinemic clamp [98]

Its essential to avoid situations that use up lots of energy (like fasting) as that can trigger the condition