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[] Glutamine has anti-inflammatory effects, activating extracellular signalregulated kinasedependent proteins for cell proliferation and gene transcription regulation

Furthermore, H.pylori may exacerbate FR-mediated mucosal damage by degrading the surface mucus layer, which is known to have FR-scavenging activity [72]

These adaptations can support survival and resistance to selected treatments, with effects varying by cell lineage, genotype, nutrient availability, and drug mechanism (Jyotsana et al., 2022)