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J Chem Ecol 31(2):247265 Borzabad RK, Sudarshana MS, Niranjan MH (2010) In vitro plant regeneration from leaf explants of Artemisia vulgaris L.-a medicinal herb

This network connects peripheral dysregulation to central neurodegeneration, demonstrating that PD etiology goes beyond local brain pathology to include systemic immunological and metabolic interactions

The second allosteric site is formed by the deep groove between the catalytic domain and the dimerization domain

These irregularities lead to energy failure characterized by decreased ATP production and an increase in lactate concentration, resulting in systemic acidosis