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Other factors are mentioned, such as kidney disease or genitourinary cancer, but are likely linked to other issues ( 5 Definition of hypertension The definition of hypertension is given according to the Common Terminology Criteria for Adverse Events (CTCAE) criteria, which ranges from grade 1 to grade 5, where grade 1 includes all adults with systolic blood pressure (SBP) ranging from 120 to 139 mmHg and DBP ranging from 80 to 89), while grade 5 indicated patient death (Table 2A)