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63 HanD.SenC

Preclinical studies in in vitro models have shown that simvastatin exerted its anti-tubercular activity through cholesterol-driven autophagy, which is mediated by the adenosine monophosphate-activated protein kinase (AMPK)mammalian target of the rapamycin complex 1 (mTORC1)TFEB axis [58] (Fig

Detrait ER, Danis B, Lamberty Y, Foerch P (2014) Peripheral administration of an anti-TNF- receptor fusion protein counteracts the amyloid induced elevation of hippocampal TNF- levels and memory deficits in mice