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Realizing this potential requires a secure, scalable software platform that integrates the LPA model with electronic health records (EHRs) to support data-driven clinical decision-making

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Abbreviations ABC: Aberrant Behavior Checklist ACC: Anterior cingulate cortex AE: Adverse event ASD: Autism spectrum disorder ATEC: The Autism Treatment Evaluation Checklist AUCB: Autologous umbilical cord blood BM: Bone marrow CARS: Childhood Autism Rating Scale CB: Cord blood CD: Cluster of differentiation CDD: Childhood disintegrate disorders CGI-I: The Clinical Global Impression Scales for the Global Improvement CGI-S: The Clinical Global Impression Scales for the Severity of Illness dlPFC: Dorsolateral prefrontal cortex DSM-5: The Diagnostic and Statistical Manual of Mental Disorders (5th Edition) DTI: Diffusion-weighted images EEG: Electroencephalography EOWPVT: Expressive One-Word Picture Vocabulary Tests EPC: Endothelial progenitor cell FIM: Functional Independence Measure Scales FSC: Fetal stem cell GARS: Gilliam Autism Rating Scale GvHD: Graft vs host disease HSC: Hematopoietic stem cell IFG: The inferior frontal gyrus ISAA: Indian Scale for Assessment of Autism IT: Intrathecal IV: Intravenous MNC: Mononuclear cell MSC: Mesenchymal stem/stromal cell NVIQ: Non-verbal IQ ORC: Ollivier-Ricci curvature PDDBI: Pervasive developmental disorder behavior inventory PDD-NOS: Pervasive developmental disorder not otherwise specified PET-CT: Positron emission tomographycomputed tomography ROWPVT: Receptive One-Word Picture Vocabulary Test RTT: Rett syndrome TNC: Total nucleated cells UC: Umbilical cord VABS: The Vineland Adaptive Behavior Scales Wee-FIM: Pediatric Version of Functional Independence Measure Scales References Ahmed LA, Al-Massri KF (2021) Directions for enhancement of the therapeutic efficacy of mesenchymal stem cells in different neurodegenerative and cardiovascular diseases: current status and future perspectives

Directions for Use: Administered by a healthcare professional via intramuscular injection