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Chronic Iron Deficiency

Cystathionine, nicotinamide, and glycine levels were higher, and lactate, GABA and choline were lower in the CSF of PTEN-WT GBM patients [190]

Oncology 90, 299306

The more commonly used class III ferroptosis inducers are FSP1 inhibitor (which inhibits FSP1 activity and reduces coenzyme Q10 production) (134), statins (which inhibit the mevalonate pathway) (135,136), and class IV ferroptosis inducers, such as heme (which increases the amount of intracellular iron in the unstable state) (137) and artemisinin (which induces ferritin autophagy, causing the release of iron in the unstable state) (138)