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(2016) 1638(Pt B):16782

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They have found that intervention with baicalin inhibited the activity of NF-B, reduced its nuclear translocation, and downregulated the expression of inflammation-related genes, thereby alleviating hepatic inflammatory responses

Such compounds act by inhibiting system x c , a transmembrane cystine-glutamate antiporter, which imports cystine (the oxidized, disulfide form of cysteine) into cells