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Description

Altered functions of natural killer cells in response to L-Arginine availability

Int Immunopharmacol (2018) 57:15764

Our study clearly demonstrated that under Hcy conditions, HMGB1/2 undergo nuclear-cytoplasmic translocation and extracellular release, independent of acetylation but mediated by K-Hcy modification, thereby linking Hcy metabolism directly to endothelial aging