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The authors suggested that the neutralization of FUS-LCD by N-terminal acetylation may disturb other interactions between the molecules as well as phase separation by changing the peptide net charge from 2 to 3 119

Besides acute phototoxicity, some photosensitizing medications also enhance epidermal mutagenesis, increasing the long-term risk of cutaneous cancer in the form of basal cell carcinoma (BCC), squamous cell carcinoma (SCC), cutaneous melanoma (CM), and cutaneous T-cell lymphoma (CTCL) [38,39]

B12 supports this process indirectly through its effects on homocysteine

accordingly, restricting fructose availability or inhibiting this metabolic pathway significantly suppresses tumor growth and enhances chemotherapy sensitivity (32)