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Yearly monitoring of B 12 status and suitable adjustment of the supplementation dose is recommended.50 For symptomatic deficiency (box 1) caused by insufficient dietary intake, intramuscular B 12 therapy is usually initiated with the aim of progressing to oral supplements once symptoms have resolved.789 Symptomatic deficiency in people with B 12 malabsorption Suggested treatment schemes differ considerably between countries

The crude order of affected systems is shown in the figure from highest prevalence to lowest prevalence according to panelists votes in survey 1

Of course, it is common for those with anemia to take iron supplements as well if necessary

These deficiencies are often due to restrictive diets, food sensitivities, and gastrointestinal issues common in ASD