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Description

In T2DM, hyperglycemia and hyperinsulinemia, coupled with decreased GLUT4 expression, 480 weaken insulin signaling and diminish glucose metabolism

Epub 2010 Jun 5

doi: 10.1023/A:1017599100641

As we get older, mitochondria accrue more and more mutations, release more and more inflammation provoking debris (Munoz-Pinto et al., 2021), countermeasures to mitigate the harm begin to fail (Lane, 2015), and keeping the microbiota healthy becomes less and less feasible