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In a study conducted in Sweden, Norway, Denmark, and Spain, on patients between 17 and 76 years old (Karantanos et al., 2010

The delivery of these vesicles to the plasma membrane involves cytoskeleton assembly/disassembly (Potokar et al., 2007) requiring ATP hydrolysis (Korn et al., Protection against oxidative stress The use of NADH through the electron transport chain for ATP production and mitochondrial Ca 2+ influx results in reactive oxygen species (ROS) production (Boveris and Chance, 5)