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These effects included downregulation of senescence-associated biomarkers, SASP suppression, and muscle fiber hypertrophy

Constitutive activation of NF-B in myeloid cells, as a result of IB deletion using the LysM-Cre system, causes more severe CNS inflammation and clinical scores in myelin oligodendrocyte glycoprotein-induced EAE, 121 whereas myeloid cell-specific deletion of IKK inhibits EAE induction associated with impaired generation of inflammatory Th1 and Th17 cells

injection, both nanotherapies (LH NP and TLH NP) showed negligible effects on bleeding (Supplementary Fig

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