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TLRs can recognize microbial-associated molecular patterns (MAMPs), such as lipopolysaccharides (LPS), and are activated by changes in the composition of gut microbiota and gut permeability (Bowman et al., 2014)

KD is an efficient treatment for pediatric drug-resistant epilepsy (DRE)

Serum liver tests should be performed prior to therapy and at frequent intervals thereafter, especially during the first six months [seeWarnings and Precautions (5.1)]

The superoxide dismutase 1 ( SOD1 ) and fused in sarcoma ( FUS ) genetic forms of ALS are exceptions as they do not develop TDP-43 aggregates, but instead show cytoplasmic SOD1 and FUS aggregates, respectively [8, 10, 11]