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If oral B12 replacement has been trialled in a person with metformin-associated B12 deficiency, I would suggest that a repeat measurement of B12 levels after 812 weeks is a good time to reassess whether absorption is adequate or whether a switch to intramuscular replacement is required

13 Best High-Potency Liquid B12 Supplement Horbaach B12 Vitamin 5000 mcg Sublingual Liquid Pros High potency 5,000 mcg dose using both methylcobalamin and cyanocobalamin for better absorption Convenient liquid dropper for fast, sublingual delivery directly into the bloodstream Clean formula Non-GMO, gluten-free, and free from wheat, yeast, milk, and lactose Cons Laboratory tested in-house but not independently third-party certified Only available in berry flavor limited option for those sensitive to flavored supplements Higher fluid volume (4 fl oz) may not be ideal for those who prefer compact packaging Form: Liquid Drops | Dosage: 1 serving daily (sublingual) | Quantity: 4 fl oz (118 ml) | Price: $9.99 | Third-party tested: No Description: Horbaach B12 Sublingual Liquid is a high-potency option that delivers 5,000 mcg of vitamin B12 per serving using a dual-form blend of methylcobalamin and cyanocobalamin

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