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These include sarcoidosis, high phosphate blood levels, high calcium blood levels, excessive vitamin D levels, arteriosclerosis with occlusion of the arteries, kidney stones, kidney disease with reduced kidney function, and allergies to vitamin D

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Whereas regulatory T cells (Tregs) mainly depend on lipid oxidation as the main source of metabolism, ROS produced during oxidative metabolism affect the differentiation of CD4 + T cells through various mechanisms ( in vivo , oxidative stress, and the harmful effects of oxidative stress on physiological functions