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However, it was not recognized at the time that evidence for the protein binding hypothesis was obtained in animals on a normal diet whereas the LPO hypothesis was derived from animals fed a vitamin E-deficient diet high in polyunsaturated fatty acids (PUFAs), i.e., in animals highly susceptibility to LPO [61]

Chung EJ

Common side effects include: Nausea Constipation or diarrhea Decreased appetite Heartburn Fatigue or dizziness B12 helps reduce fatigue and may ease gastrointestinal discomfort for some users