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Finally, quality of life, as assessed by RAND36, was similar in most dimensions to a large control population with chronic disease in spite of the excellent glycemic control

While vitiligo primarily affects skin pigmentation, it can have other impacts

10.1146/annurev.bi.45.070176.003015

Like CaMKK2, the PKA signalling pathway is also considered to play a key role in the pathogenesis of bipolar disorder, as increased cyclic AMP levels and PKA activity have been frequently observed in post-mortem brains and peripheral cells of bipolar disorder patients [58,59,60,61]