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In further support of this, Spearman correlation analysis indicated that although there was no significant correlation between the 2- and 4-hydroxyestrogens and the 4-hydroxyestrogen DNA-adducts or glutathione conjugates, the nature of the relationship between these metabolites changed from positive in the control women to negative in the COC users (Fig

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The mtDNA T8993G (NARP) mutation results in an impairment of oxidative phosphorylation that can be improved by antioxidants