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Notably, substantial heterogeneity was appreciated between studies analyzed

One illustrative modified Dipththeria toxin is DT388, a DT in which the carboxyl terminal sequence beginning at residue 389 is removed see, e.g., Chaudhary et al

doi: 10.1371/journal.pone.0303449 125 SpierA.ConnorM

Daolin Tang, [email protected] This article was submitted to Neuro-Oncology and Neurosurgical Oncology, a section of the journal Frontiers in Oncology Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers