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Several types of allelic variation have been identified within classes, with GSTM1 -null, GSTT1 -null and GSTP1-Ile105/Ile105 conferring impaired catalytic activity

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So, the point about the polygenic risk score is for each of these conditions, could be colon cancer, could be atrial fibrillation, validated to the health, theres hundreds of variants that are linked to that condition

Abbreviations TBI: Traumatic brain injury ALC: Acetyl-L-carnitine NS: Normal saline CCI: Controlled cortical impact MRI: Magnetic resonance imaging 1 H-MRS: Proton magnetic resonance spectroscopy References Injury GBDTB, Spinal Cord Injury (2019) Global, regional, and national burden of traumatic brain injury and spinal cord injury, 19902016: a systematic analysis for the global burden of disease study 2016