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The possible interference of the vector with Prx II gene expression was analyzed by comparing Prx II protein and mRNA levels by western blotting and real time PCR in both control (mock) and Prx II-knockdown (sh Prx II) cells (Fig

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These dysfunctions may arise from impaired pyruvate dehydrogenase (PDH) function identified in muscle cells (390) and serum (184), as well as reduced plasma coenzyme Q10 (CoQ10) levels in ME/CFS blood and plasma (372, 391) that is inversely associated with fatigue severity (391)