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Statements Author contributions HL: Conceptualization, Methodology, Visualization, Writing original draft, Writing review & editing, Funding acquisition

To determine protection against cell dehydration during double stress, proline content was used as a marker (Fig

Thus, the results generated the hypothesis that chronic enhancement in the rate of active transport in AD (Ronquist and Waldenstrm, 2003) leading to the increase in ATP and 2,3-DPG hydrolysis and can increase in Hb affinity to oxygen, loss of adequate oxygen delivery to tissues that may be one of the factors contributing to brain hypoxia (Aliev et al., 2004), glucose hypometabolism, and memory dysfunction in AD