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The metabolic syndrome and microvascular complications in a murine model of type 2 diabetes

It blocks ACE activity, reduces ROS production, and limits NF-kB activation

doi: 10.1053/j.gastro.2013.05.048

Ferroptosis markers such as CHAC1 and TFRC 29 increased despite only partial reduction of GPX4 transcripts, suggesting activation of ferroptosis in vivo (Fig