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4.3 Pharmacological interventions Pharmacological interventions for sarcopenia in CKD are an area of active research, though current evidence is limited, and the optimal strategies are not yet firmly established

They reflect different protocol arms within the same trial

The Asp9 forms a hydrogen bond with Arg370, while Ser8 and Ser11 of Tirzepatide form a network of hydrogen bonds involving the receptor residue Glu288, Arg 289, and Asn290