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The mechanism of action, involving natural beta-3 adrenergic receptors and lipolytic pathways, suggests that chronic use is unlikely to produce novel safety concerns beyond what was observed in clinical trials

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As a radiotherapeutic agent, the sdAb 2F8 radiolabeled with the emitter 177 Lu, 177 Lu-DTPA-2F8 showed dose-dependent tumor regression and survival in myeloma bearing mice [108]